Lewis Center is an unincorporated community in northwestern Orange Township, Delaware County, Ohio, United States, located between Columbus and Delaware. Its ZIP code is 43035. Although Lewis Center is a small community, its ZIP code encompasses a number of shopping centers and retail establishments that line U.S. Route 23 in the nearby vicinity. The Lewis Center area lies on the east side of the Olentangy River, across from the city of Powell, and west of Alum Creek State Park.