Big Pine (formerly, Bigpine) is a census-designated place (CDP) in Inyo County, California, United States. Big Pine is located 15 miles (24 km) south-southeast of Bishop, at an elevation of 3990 feet (1216 m). The population was 1,350 at the 2000 census. The Big Pine Band of Owens Valley Paiute Shoshone Indians of the Big Pine Reservation operates their tribal headquarters from here.