Durham is a town in Strafford County, New Hampshire, United States. The population was 12,664 at the 2000 census. Durham is home to the University of New Hampshire. The primary settlement in town, where more than 71% of the population resides, is defined by the U.S. Census Bureau as the Durham census-designated place (CDP) and includes the densely-populated portion of the town centered on the intersection of New Hampshire Route 108 and Main Street and including the university which dominates the town.